Professor Philip Duffus and Family

W4Philip_Duffus_and_Family_1997_large.jpg (152480 bytes)
Graduation day - Bristol University 1997


CURRICULUM VITAE

of

 WILLIAM PHILIP HOLWELL DUFFUS


  INDEX 

Page

Background and Education - 2

Career in brief - 3

Career in more detail - 3

Teaching responsibilities and Experience - 5

Research Interests - 6

Publications - 7

Background and Education 

Surname DUFFUS

Forenames William Philip Holwell

Date of Birth 27 April 1943

Marital status Married

Children Two Julie Anne Holwell born 3 April 1975

Philippa Holwell born 26 March 1985

Nationality British

 

Qualifications

1966 B.V.Sc. (University of Liverpool)

1966 M.R.C.V.S. (Royal College of Veterinary Surgeons)

1969 Ph.D. (University of Liverpool)

1979 M.A. (University of Cambridge)

 

Secondary Education

1951 - 1961 Attended Bedford School

Obtained 10 ordinary level School Certificates

Obtained 4 advanced level School Certificates 

 

University Education

1961 - 1966 University of Liverpool, School of Veterinary Medicine

Obtained degree of B.V.Sc.

Awarded Pathology Prize

Awarded Best Student of the Year Prize

1966 - 1969 University of Liverpool, Department of Veterinary Pathology.

Immunological Research, obtained Degree of Ph.D. in 1969

Title of Thesis: A Study on Humoral and Cellular Immune Responses in Chickens and Rats to Bacterial and Heterologous Erythrocyte Antigens

Career History In Brief

1990 - present Professor of Veterinary Medicine and Head of Bristol University Clinical Veterinary School

1987 - 1990 Deputy Head of Cambridge University Veterinary School

1984 - 1990 Tutor and Senior Tutor, Clare Hall College, Cambridge

1980 - 1990 Lecturer, Department of Clinical Veterinary Medicine, University of Cambridge

1981 - 1990 Official Fellow, Clare Hall College, Cambridge

1977 - 1981 Research Fellow, Clare Hall College, Cambridge

1977 - 1980 Senior Research Associate at the Department of Pathology, University of Cambridge

1972 - 1977 Immunologist at the Kenyan National Veterinary Research Laboratories, Kenya. Employed firstly by the FAO of the United Nations and later by the ODA British Aid Scheme (Crown Agents)

1970 - 1972 Medical Research Council Research Lecturer in Department of Pathology, University of Bristol

1969 - 1970 Post-Doctoral Fellow, University of Liverpool 

 

Career posts in more detail

A Professor of Veterinary Medicine and Head of Bristol University Clinical Veterinary School

1990 - present

Budget holder and "Chief Executive " of one of Europe's leading Clinical Veterinary Schools. Soon after taking up this post in 1990 I embarked on a radical reorganisation of the Clinical Veterinary School which up to that moment was a collection of disparate and relatively small departments. The Clinical School at Bristol now consists of nearly 200 staff (academic and support), together with over 50 post graduate students studying for a Ph.D (many from overseas) and between 70-80 Veterinary undergraduates in every year of a 5 year course. The reorganisation resulted in a single Department of Clinical Veterinary Science with four academic divisions:

Animal Health and Husbandry

Companion Animals

Food Animal Science

Molecular and Cellular Biology

The Veterinary School is assessed by the public, the academic community and our paymasters (HEFC) on the basis of three "outputs". These outputs are: teaching, research and clinical work. Within the new structure formed at Bristol Veterinary School these three "outputs" formed the basis of three major matrix committees that have both financial and organisational matters delegated to them:

Teaching Committee

Research Committee

Hospital Committee

The reorganisation at Bristol Veterinary School also involved a major building expansion including:

New Small Animal Hospital (one of the largest in the UK)

New Equine Diagnostic Centre (serving the south west, Wales and central England).

New lecture theatres

Extensive computerisation and networking of site.

I have been responsible for heading-up all these projects and developments including the initial planning, production of detailed business plans, securing funding, selection of contractors etc.

The main duties of my current post can be summarised:

a) Responsible to the Vice Chancellor of Bristol University for the annual budget of the Department, currently just over 10 million per annum

b) Co-ordinating the securement of over 3.5 million per annum for research within the Department

c) Overall responsibility for delivering an effective course to Veterinary undergraduates

d) Providing academic leadership to the Clinical Veterinary School

e) Overall responsibility for the management and career develpoment of nearly 200 academic and support staff

Current annual salary is 43,442 together with the British Universities contributory superannuation scheme (USS).

 

B Deputy Head of Cambridge University Veterinary School, Lecturer, Official Fellow and Senior Tutor, University of Cambridge
1980-1990

My ten year period of work at Cambridge Veterinary School combined a research and teaching career as a lecturer, a College career as Official Fellow and Senior Tutor and in the last few years a management career as Deputy Head of Cambridge Veterinary School. My research group included both overseas post graduate students and experimental work on diseases found in East and Central Africa (eg East Coast Fever and Trypanosomiasis). My position as Senior Tutor gave me the major responsibility for the selection, processing and overseeing of all the post graduate students, the majority of whom were from overseas.

I left Cambridge University on appointment to a Chair at Bristol University.

 

C Senior Research Associate, Department of Pathology, University of Cambridge
1977-1980

This was a three year full-time research post taken up after my initial return from the six years work in East Africa. The work was funded by the Wellcome Trust and Agricultural Research Council.

I left to take up a tenured position within Cambridge University.

 

D Immunologist at the Kenyan National Veterinary Research Laboratory
1971-1977

For the first three years in Kenya I was employed by the FAO of the United Nations as team leader in immunology within a project investigating the prevalence of tick-borne diseases within Kenya. The work also involved training of both professional and support staff including training abroad for a number of Kenyan staff.

The following three years of work funded by the British Government concentrated on developing the immunology laboratory at the Veterinary Research Centre and establishing a number of diagnostic tests etc. for use in the field and laboratory.

I left this job to return to an academic career in Britain.

 

Teaching Responsibilities and Experience

Undergraduate

a) Lecturing

Veterinary Immunology

An applied course given to veterinary students after their basic immunology course in the Medical Science Tripos.

Epidemiology

A course given to veterinary students before they begin their species medicine courses, and intended to introduce the concepts of epidemiology and disease control.

Cattle Medicine

Lectures forming part of the combined cattle course. Subjects covered include all neonatal calf diseases, enzootic calf pneumonia, salmenellosis, respiratory disease in adults, gastro-intestinal diseases in adults and fluid therapy.

Comparative Immunology

A short course given to pre-clinical veterinary, medical and natural science students.

 

b) Clinical and practical teaching

Small group teaching in clinical examination, preventative medicine, the use and application of computer-based (eg Daisy) programmes and immune-mediated diseases.

c) Examining

Assessor, Examiner and Chairman of Examiners for all medical subjects in the Final Veterinary Examination at the University of Cambridge and Bristol.

Postgraduate

I have personally supervised 12 PhD students comprising individuals from both both home and overseas (including one from Kenya). I have also examined several PhD dissertations for the Universities of Bristol, Cambridge, Edinburgh, Liverpool, Glasgow and London.

 

Research Interests 

My research group consisted of post-doctoral workers, research assistants, Ph.D.students, laboratory technicians and animal technicians, together with a regular number of visiting scientists. Over the last ten years my research has been focused in the following main areas:

1. A study on the immune response against helminth and nematode parasites

This includes studying the eosinophil-mediated antibody-dependent destruction of parasites; the isotype and sub-isotype of antibody responsible; the influence of mediators such as ECF-A and interleukins; the characterisation and biological activity of granule contents from eosinophils and neutrophils, especially cationic proteins; and purification of surface antigens from the parasites both to provide sensitive and specific serological assays, as well as possible immunogens for vaccination.

2. A research project involving both basic and applied immunology to study the defense mechanisms of the calf respiratory tract and its importance in enzootic pneumonia of calves

This includes working on viruses such as BHV1, PI3 and RSV; producing highly sensitive ELISA tests for each virus; examining the potential of calf leucocytes to destroy virus infected targets in both antibody-dependent (ADCC) and antibody-independent (CTL and NK) assays; and producing a sensitive and reliable 3H-uridine incorporation assay for bovine interferon (IFN).

3. A study of the anti-viral and immunomodulating effects of recombinant bovine IFNa, IFNg and tumour necrosis factor (TNF)

These recombinant lymphokines and monokines are assessed in vitro for their effect on the recruitment and activation of bovine NK cells. Experiments are also done on delivery systems in vivo to induce high levels of anti-viral activity in the upper and lower respiratory system of calves following inhalation of an aerosol of IFNa. Some of this work has involved the study of individual field cases and outbreaks in an effort to bridge the gap between laboratory based research, the actual disease problem itself and the needs (diagnostic and therapeutic) of the clinicians.

4. Equine Herpes Virus (EHV1) and foal immunology

A major part of the research effort of my group was in the area of producing SPF (EHV1 free) foals and establishing a totally susceptible equine model for EHV1 infection. Various recombinant and purified glycoprotein preparations tested by various routes for their potential as candidate vaccines.

In addition, the IFN response and isotype and sub-isotype antibody response in serum and nasal mucous in response to EHV1 infection was studied. At the cellular level specific T cell transformation, NK activity and neutrophil-mediated antibody-dependent cytotoxicity (ADCC) were also studied. All these parameters are included in a battery of assays in an additional study on the development of immune competence in the neonatal foal.

5. Monoclonal antibodies

A panel of monoclonal antibodies (Mabs) have been made against canine lymphocytes and a retrovirus-infected canine lymphoid cell line. In addition the canine NK cell assay has been established using the latter target, and was studied in a series of clinical tumour cases.

A panel of Mabs has also been recently made against canine IgG sub-isotypes. In addition another panel of Mabs has been produced against equine lymphocytes and equine immunoglobulins.

6. Use of Bovine Hyperimmune Colostrum for Treatment and Prevention of Disease

Techniques have been evolved to hyperimmunize cattle against selected pathogens from both domestic animal and human diseases. Assays have been developed to quantify the specific immunoglobulin content of the colostral preparations as well as assessing the anti-pathogen activity of the samples in patients (eg in AIDS patients suffering from cryptosporidial infection).

7. AFRC link programme with the Institute of Animal Physiology, Babraham

This link programme studied the role and fate of the large population of null T lymphocytes in the young pig. This work was firstly on their potential differentiation pathways using a combination of Mabs and cDNA probes; secondly on their functional role in assays such as NK cell killing; thirdly on their origins, phenotypic changes and migration in vivo.

8. Innovative Vaccines

A molecular biological approach to developing an innovative approach to vaccination of cattle involving a recombinant herpes viral vector with insertion sites for both bovine cytokine genes as well as individual pathogen genes. 

PUBLICATIONS

 ALLAN, D, DUFFUS, W.P.H. and HIGGINS, D.A. ( 1968) Measurement of antigen-antibody complexes in Salmonella gallinarum infection.Immunology 14, 575.

DUFFUS, W.P.H. and ALLAN, D. (1968) A study of the immunological response in chickens to the somatic antigen of Salmonella galllinarum. Immunology 15, 653.

DUFFUS, W.P.H. and ALLAN, D. (1969) A study of the ontogeny of specific immune responsiveness amongst circulating leucocytes in the chicken. Immunology 16, 337.

DUFFUS, W.P.H. and ALLAN, D. (1971) The kinetics and morphology of the rosette-forming cell response in the popliteal lymph nodes of rats. Immunology 20, 345.

ALLAN, D., ELSON, J., DUFFUS, W.P.H. and JAMES, K. (1971) The loss of the immunosuppressive properties of antilymphocyte globulin following absorption with immunizing antigen (SRBC) Clinical and Experimental Immunology 8, 101.

ALLAN, D. and DUFFUS, W.P.H. (1971) The immunopathology in fowls (Gallus domesticus) of acute and subacute Salmonella gallinarum infection. Research in Veterinary Science 12, 140.

TAYLOR, R.B., DUFFUS, W.P.H., RAFF, M.C. and DE PETRIS, S. (1971) Redistribution and pinocytosis of lymphocyte surface immunoglobulin molecules induced by anti-immunoglobulin antibody. Nature 233, 225.

ELSON, C.J., ALLAN, D., ELSON, J. and DUFFUS, W.P.H. (1972) The relationship between the morphology of rosette-forming cells and their mode of rosette formation. Immunology 22, 291.

DUFFUS, W.P.H. and WAGNER, G.G. (1974) The specific immune response in the lymph nodes of cattle undergoing Theileria parva infection, as determined by the rosette test.

Parasitic Zoonoses, Clinical and Experimental Studies (ed. by E.J.L. Soulsby), p. 85, Academic Press, New York.

WAGNER, G.G. and DUFFUS W.P.H. (1974) Anti-lymphocyte antibody responses in cattle after inoculation with Theileria parva infected lymphoblastoid cell lines.

Parasitic Zoonoses, Clinical and Experimental Studies (ed. by E.J.L. Soulsby), p.97, Academic Press, New York.

DUFFUS, W.P.H. and WAGNER, G.G. (1974) Immunoglobulin response in cattle immunised with Theileria parva stabilate. Parasitology 69, 31.

WAGNER, G.G., DUFFUS, W.P.H. and BURRIDGE, M.J. (1974) Immunoglobulin response in cattle to Theileria parva antigens. Parasitology 69, 43.

WAGNER, G.G., BROWN, C.G.D., DUFFUS, W.P.H., KIMBER, C.D., CRAWFORD, J.G. and LULE, M. (1974) Immunochemical studies on East Coast Fever. Partial segregation and characterisation of Theileria parva schizont antigen. Journal of Parasitology 60, 848.

DUFFUS, W.P.H., WAGNER, G.G. and KIMBER, C.D. (1974) Immunochemical studies on East Coast Fever. Development of an indirect haemagglutination assay using Theileria parva piroplasm antigen. Journal of Parasitology 60, 860.

WAGNER, G.G., DUFFUS, W.P.H., KIMBER, D.C. and LULE, M. (1974) Immunochemical studies on East Coast Fever. Partial segregation and characterization of Theileria parva piroplasm antigen. Journal of Parasitology 60, 854.

WAGNER, G.G., DUFFUS, W.P.H., AKWABI, C., BURRIDGE, M.J. and LULE, M.(1975) The specific immunoglobulin response in cattle to Theileria parva (Muguga) infection. Parasitology 70, 95.

DUFFUS, W.P.H., PRESTON, J.M. and STAAK, C.H. (1975) Initial fractionation of adult Schistosoma bovis antigen for diagnosis of infection in cattle. Journal of Helminthology 49, 1.

PRESTON, J.M. and DUFFUS, W.P.H. (1975) Diagnosis of Schistosoma bovis infection in cattle by an indirect haemagglutination test. Journal of Helminthology 49, 9.

NEWSON, R.M., DUFFUS, W.P.H. and KILTZ, H. (1975) East Coast Fever: Cross-immunity trials. Food and Agriculture Organisation of the United Nations, Rome.

DUFFUS, W.P.H. (1975) Some aspects of the immunology of tick-borne cattle diseases in Kenya. Food and Agricultural Organisation of the United Nations, Rome.

DUFFUS, W.P.H., NEWSON, R.M. and KILTZ, H. (1975) An epizootiological survey of tick-borne cattle diseases in Kenya. Food and Agricultural Organisation of the United Nations, Rome.

DUFFUS, W.P.H., BUTTERWORTH, A.E.B., WAGNER, G.G., PRESTON, J.M. and FRANKS, D. (1978) Antibody-dependent cell-mediated cytotoxicity in cattle. Activity against 51Cr labelled chicken erythrocytes coated with protozoal antigen. Infection and Immunity 22, 492.

DUFFUS W.P.H., WAGNER, G.G. and PRESTON, J.M. (1978) Initial studies on the properties of a bovine lymphoid cell culture line infected with Theileria parva. Clinical and Experimental Immunol. 34, 347.

DUFFUS, W.P.H. and WAGNER, G.G. (1980) Comparison between certain serological tests for diagnosis of East Coast Fever. Veterinary Parasitol. 6, 313.

DUFFUS, W.P.H., THORNE, K.J.I. and OLIVER, R.C. (1980) Killing of juvenile Fasciola hepatica by purified bovine eosinophil proteins. Clinical and Experimental Immunol. 40, 336

DUFFUS, W.P.H. and FRANKS, D. (1980) In vitro effect of immune serum and bovine granulocytes on juvenile Fasciola hepatica. Clinical and Experimental Immunol. 41, 430.

DUFFUS, W.P.H. and FRANKS, D. (1981) The interaction in vitro between bovine immunoglobulin and juvenile Fasciola hepatica. Parasitology 82, 1.

TOWNSEND, J.A. and DUFFUS, W.P.H. (1982) Trypanosoma theileri: antibody-dependent killing by purified populations of bovine leucocytes. Clinical and Experimental Immunol. 48, 289.

TOWNSEND, J.A., DUFFUS, W.P.H. and GLAUERT, A.M. (1982) An ultra-structural study of the interaction in vitro between Trypanosoma theileri and bovine leucocytes. J. Cell Science 56, 389.

TOWNSEND, J.A., DUFFUS, W.P.H. and LAMMAS, D.A. (1982). The importance of competitive binding in the detection of antigen-specific bovine isotypes and sub-isotypes by the micro-ELISA. Research Veterinary Science 33, 319.

LAMMAS, D.A. and DUFFUS, W.P.H. (1982) The use of the ELISA to detect antigen release from juvenile Fasciola hepatica. Current Topics in Veterinary Medicine and Animal Science 22, 52.

DUFFUS W.P.H. (1982) Applications of the enzyme linked immuno-adsorbant assay (ELISA) in veterinary protozoology. Current Topics in Veterinary Medicine and Animal Science 22, 72.

LAMMAS, D.A. and DUFFUS, W.P.H. (1983) The shedding of the outer glycocalyx of juvenile Fasciola hepatica. Veterinary Parasitology 12, 165.

DUFFUS, W.P.H. (1983) Steptococcal meningitis in pigs: the immune response and its implications for diagnosis and possible vaccination.

In: Some Diseases of Emerging Importance to Community Trade. Eds. J.R. Walton, E.G. White and S.A. Hall. European Communities Commission, Luxemburg.

THORNE, K.J.I., NORMAN, J.N., HAYDOCK, S.F., LAMMAS, D.A. and DUFFUS, W.P.H. (1984) Antibody-dependent cell-mediated cytotoxicity against IBR-infected bovine kidney cells by ruminant and human neutrophils: the role of lysosomal cationic protein. Immunology 53, 275.

DUFFUS, W.P.H. (1984) Isotope-based immunological techniques: their use in assessment of immune competence and the study of immune responses to pathogens. In: Nuclear techniques in tropical animal diseases and nutritional disorders. Ed. I.A.E.A. Vienna.

CLIFTON-HADLEY, F.A., ALEXANDER, T.J.L., UPTON, I. and DUFFUS, W.P.H. (1984) Further studies on the subclinical carrier state of Streptococcus suis type 2 in pigs. Veterinary Record 114, 513.

WARDLEY, R.C. and DUFFUS, W.P.H. (1984) The role of immunity in virus infections. Development of the immune response, influence of both host and virus.

In: Cell Mediated Immunity p. 312, Ed. P.J.Quinn. European Communities Commission, Luxemburg.

DUFFUS, W.P.H. and WARDLEY, R.C. (1984) Cell-mediated immunity in viral diseases: effector mechanisms.

In: Cell Mediated Immunity p. 320, Ed. P.J.Quinn. European Communities Commission, Luxemburg.

LAMMAS, D.A., DUFFUS, W.P.H. and TAYLOR, D.W. (1985) Identification of surface proteins of juvenile stages of Fasciola hepatica. Research Veterinary Science 38, 248.

TOWNSEND, J.A. and DUFFUS, W.P.H. (1985) Antibody-dependent cellular cytotoxicity of Trypanosoma theileri by purified bovine isotypes and sub-isotypes. Parasite Immunology 7, 179.

GLAUERT, A.M., LAMMAS, D.A. and DUFFUS, W.P.H. (1985) Ultrastructural observations on the interaction in vitro between bovine eosinophils and juvenile Fasciola hepatica. Parasitology 91, 459.

O'BRIEN, J.K. and DUFFUS, W.P.H. (1986) Pasteurella haemolytica cytotoxin: susceptibility of bovine leucocytes. Veterinary Microbiology 13, 321.

O'BRIEN, J.K. and DUFFUS, W.P.H. (1987) Neutralization of Pasteurella haemolytica leucotoxin by bovine immunoglobulins British Veterinary J. 143, 439.

TOWNSEND, A.J., DUFFUS, W.P.H. and WILLIAMS, D.J.L. (1988) Immune production of interferon by cultured peripheral blood mononuclear cells from calves infected with BHV1 and PI3 viruses. Research Veterinary Science 45, 198.

TOWNSEND, A.J., DUFFUS, W.P.H. and WILLIAMS, D.J.L. (1988) The effect of age of cattle on the in vitro production of interferon by peripheral blood mononuclear cells. J. Comparative Pathology 99, 169.

DUFFUS, W.P.H. (1988) Immunity to Infection. In Veterinary Clinical Immunology, p. 135. Eds. R.E.W. Halliwell and N.T. Gorman. W.B. Saunders, London.

DUFFUS, W.P.H. (1988) Immunoprophylaxis. In Veterinary Clinical Immunology, p. 205. Eds. R.E.W. Halliwell and N.T. Gorman. W.B. Saunders, London.

Petrovskis, E.A., Duffus, W.P.H., Thomsen, D.R., Meyer, and Post L.E. (1988) Sequence of pseudorabies virus and infectious bovine rhinotracheitis virus glycoprotein H genes. 13th Int. Herpesvirus Workshop, p. 217.

Holmes, M., Duffus, W.P.H. and Gorman, N.T. (1989) Natural cytotoxicity in the dog: description of two new allogeneic tumour targets. Veterinary Immunology and Immunopathology 23, 122.

Holmes, M., Duffus, W.P.H. and Gorman, N.T. (1989) Monoclonal antibodies identifying cell surface proteins on a canine lymphoma cell-line. Veterinary Immunology and Immunopathology.

DUNCAN, I.A. BINNS,R.M.and DUFFUS W.P.H. (1989) The null T cell in pig blood is not an NK cell. Immunology 68, 392.

O'BRIEN, M.A. and DUFFUS W.P.H. (1990) The effects of Dexamethasone, Betamethasone, Flunixin and Phenylbutazone on bovine natural killer cell cytotoxicity. Veterinary Pharmocology and Therapeutics 13, 292.

O'BRIEN, M.A., HOLMES, M.A. LUNN, D.P.and DUFFUS, W.P.H. (1991) Evidence for MHC class-I restricted cytotoxicity in the one-way primary mixed lymphocyte reaction. Equine Vet. J. 12, 30.

MEYER, A.L., PETROVSKIS, E.A., DUFFUS, W.P.H. et al (1991) Cloning and sequence of an infectious bovine rhinotracheitis virus (BHV1) gene homologous to glycoprotein H of herpes simplex virus. Biochimica et Biophysica Acta 1090, 267.

LUNN, D.P., HOLMES, M.A. GIBSON, J, FIELD, H.J., KYDD, J.H. and DUFFUS, W.P.H. (1991) Haematological changes and equine lymphocyte subpopulation kinetics during primary infection and attemped re-infection of specific pathogen free foals with EHV-1. Equine Vet. J. 12, 35.

DUFFUS, W.P.H. (1992) Immunological Fundamentals. In Bovine Medicine ed. A.H. Andrews. Blackwell Scientific Publications. p797.

CHONG, Y.C. and DUFFUS, W.P.H. (1992) Immune responses of specific pathogen free foals to EHV-1 infection. Veterinary Microbiology 32, 215.

CHONG, Y.C., DUFFUS, W.P.H. and HANNANT, D. (1992) Natural killer cells in normal horses and specific pathogen free foals infected with equine herpesvirus. Veterinary Immunology and Immunopathology 33, 103.

BINNS, R.M., LICENCE, S.T., WOODING, F.B.P. and DUFFUS, W.P.H. (1992) Active lymphocyte traffic induced in the periphery by cytokines and phytohemagglutinin: three different mechanisms? Eur. J. Immunol. 22, 2195.

O'BRIEN, M.A., HOLMES, M.A. and DUFFUS, W.P.H. (1992) In vitro production of specific antibody by equine peripheral blood mononuclear cells using tetanus toxoid as a recall antigen. Res. Vet. Science 53, 184.

LUNN, D.P., HOLMES, M.A. and DUFFUS, W.P.H. (1992) Three monoclonal antibodies identifying antigens on all equine T lymphocytes, and two mutually exclusive T-lymphocyte subsets. Immunology 74, 251.

MAZZA, G., DUFFUS, W.P.H., ELSON, C.J. et al (1993) The separation and identification by monoclonal antibodies of dog IgG subclasses. J. Immunol. Methods 161, 193.

LUNN, D.P., HOLMES, M.A. and DUFFUS, W.P.H. (1993) Equine T lymphocyte MHC class-II expression: variation with age and subset. Veterinary Immunology and Immunopathology 35, 225.

LUNN, D.P., HOLMES, M.A. and DUFFUS, W.P.H. (1994) Polymorphic expression of an equine T lymphocyte and neutrophil subset marker. Veterinary Immunology and Immunopathology 42, 83

MAZZA, G., WHITING, A.H., DAY, M.J. and DUFFUS, W.P.H. (1994) Development of an ELISA for the detection of IgG subclasses in the serum of normal and diseased dogs. Res. Vet. Science 57, 133.

MAZZA, G., WHITING, A.H., DAY, M.J. and DUFFUS, W.P.H. (1994) Preparation of monoclonal antibodies specific for the subclasses of canine IgG. Res. Vet. Science 57, 140.

FOSTER, A.P., DUFFUS, W.P.H., SHAW, S.E. and GRUFFYDD-JONES, T.J. (1995) Studies on the isolation and characterisation of a reaginic antibody in the cat. Res. Vet. Science 58, 70.

 

Over 35 papers have been presented on research findings mostly to immunology and parasitology meetings.

  

Refereeing and editorial experience

1983 - 1987 Scientific Editor Veterinary Immunology and Immunopathology.

1984 - present Scientific Editor Research in Veterinary Science.

In addition I regularly referee for several other scientific journals.


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